Principal Immuno-oncologist – Therapeutics Discovery

Job Category:
Pharmaceuticals / Biotechnology / Forensics / Medical Devices
Job Type:
Permanent
Region:
South East
Town:
South East England
Salary Description:
Negotiable + excellent benefits
Posted:
24/08/2017
Recruiter:
SCI Recruitment for Scientists
Job Ref:
19608

Principal Immuno-oncologist – Therapeutics Discovery

Ref: 19608


Our client is at the forefront of research and development into leading-edge immuno-oncology (IO) therapeutics. Continued expansion means they now wish to appoint an experienced scientist to their experienced team.


They require a technical specialist who uses their expertise to enhance in house immune-oncology experimental capabilities by establishing and training scientists in IO techniques/models. You will lead target validation and disease positioning studies in immune-oncology alliances and experimental development of bespoke cell-based assays and disease-relevant in-vitro models to enable compound profiling and mechanism of action studies.  You’ll provide strategic input into existing and future IO alliances, and interact with alliance partners/academic collaborators.


Key Duties and Responsibilities

• Lead by example to establish, and train scientists in novel techniques and models to enhance IO experimental capabilities 

• Provide technical support for IO team and be accountable for quality data delivery

• Oversee design and interpretation of target validation studies using tool compounds, gene knockdown and gene editing approaches in cancer cell lines, primary cells and immune-relevant co-culture systems

• Oversee development and interpretation of phenotypic analyses in cancer and immune cells

• Review and critically appraise oncology and immunology literature and unpublished research to identify novel targets, signalling pathways and/or biomarkers

• Provide strategic input into multitude of IO projects and alliances; may involve individual project leadership responsibility


Suitable candidates will have a PhD in biological sciences, molecular biology or equivalent with significant postdoctoral experience in immunology and/or oncology research. A demonstrable track record of translational research achievement is required. Experience with the following is required:

• Target validation approaches and techniques (siRNA, shRNA, CRISPR, overexpression, tool compounds)

• Cell culture techniques plus primary cell maintenance and handling

• Phenotypic assays (cell proliferation, apoptosis, colony forming assays)

• Immunology techniques


Ideally you will also have Research experience in pharma/biotech with experience in managing a scientific team and of project leadership.


Role: Permanent

Location: South East England

Salary: Negotiable + excellent benefits


For more science jobs, go to www.sci-search.com 


Contact Details:
SCI Recruitment for Scientists
Tel: 01606 818290
Contact: Andy Cuthbert
Email:

You may return to your current search results by clicking here.

This website uses cookies. Read our cookie policy for more information. By continuing to browse this site you are agreeing to our use of cookies.