Principal Immunologist – Therapeutics Discovery
Our client is at the forefront of research and development into leading-edge immuno-oncology (IO) therapeutics. Continued expansion means they now wish to appoint an experienced lead immunologist to their dedicated team.
They require a technical specialist who uses their experience to oversee the lab work of a team of lab based immunologists, direct design and interpretation of the data by being close enough to the techniques by reason of very recent or ongoing lab based experience.
They also need to have enough insight into experimental immunology to be able to suggest and advise on additional techniques from their own direct experience and have a good network externally of expert immunologists who they can call on to provide further advice.
This means they require someone who has worked in lab immunology at postdoc level for at least 5 years, using their knowledge to enhance in house immune-oncology experimental capabilities by establishing and training scientists in IO techniques/models.
You will lead target validation and disease positioning studies in immune-oncology alliances and experimental development of bespoke cell-based assays and disease-relevant in vitro models to enable compound profiling and mechanism of action studies.
You’ll provide strategic input into existing and future IO alliances, and interact with alliance partners/academic collaborators.
Suitable candidates will have a PhD in biological sciences, molecular biology or equivalent with significant postdoctoral experience in immunology research. A demonstrable track record of translational research achievement is required. Experience with the following is required:
• Target validation approaches and techniques (siRNA, shRNA, CRISPR, overexpression, tool compounds)
• Cell culture techniques plus primary cell maintenance and handling
• Phenotypic assays (cell proliferation, apoptosis, colony forming assays)
• Immunology techniques
Ideally you will also have Research experience in pharma/biotech with experience in managing a scientific team and of project leadership.
Location: South East England
Salary: Negotiable + excellent benefits
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