Research Associate, Viral Vectors and Process Development
Our Client is a vaccine research organisation currently involved in clinical programs for therapeutic infectious diseases indications. Due to expansion they are seeking a research biologist.
You will play an integral role in conducting bench studies for both vector development and for process development to progress the adenovirus vaccine vector platform. You will ensure that the studies, tests and procedures performed in the laboratory follow quality procedures for all aspects of work.
ESSENTIAL DUTIES AND RESPONSIBILITIES:
- Conduct laboratory work involved in the design, construction, growth, and evaluation of viral vector vaccine candidates
- Assist in ordering supplies, making reagents and maintaining the laboratory in order to conduct necessary experiments
- Maintain and evaluate both mammalian and bacterial cell cultures for growth conditions, DNA purification and viral vector production
- Assist in studies to optimize the ability to manufacture adenoviral-vectored vaccines, such as evaluation of alternative systems, host or vector gene deletions or insertions, viral culture yield, systems for viral growth, etc.
- Evaluate and perform analytic assays to determine the quality, yield, stability, etc. of specific candidates or of specific manufacturing process conditions.
- Work under GLP-like conditions, with the appropriate requisite training, documentation, and attention to following defined Operating Procedures or Work Flow diagrams
- Ensure that the laboratory and activities comply with GLP-like standards and that all results produced are reviewed and presented appropriately.
QUALIFICATIONS AND REQUIREMENTS:
- Minimum of a Bachelor’s degree in the biological sciences
- At least 2 years of relevant work experience, ideally in industry, with demonstrated experience in laboratory bench work with cell culture systems
- Proficient in conducting research using a variety of methodologies; e.g., ELISA, Western blot, viral growth curves, viral titers, transfections, PCR, DNA sequence interpretation
- Excellent writing and communication skills; ability to understand and communicate scientific information; proficiency in Powerpoint, formatting charges, graphic displays and tables
- A self-starter with the ability to work in a fast-paced environment and adapt quickly to changing needs and priorities; proven ability to prioritize and manage multiple tasks simultaneously.
Location: South East England
Salary: Negotiable + Benefits
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