Associate Scientist - Immunology/Mass Spectrometry
Based South East
Attractive, negotiable salary + Benefits
Our client is a well-funded, early stage biotech currently in ‘stealth mode’, which has identified novel tumour-specific antigens derived from reactivated endogenous retroviral sequences. We have shown by immunopeptidomics that these antigens are presented by MHCI on the surface of tumour cells and are now looking to further characterise their immunogenicity. The company is using these foundational discoveries to enable the development of a range of pharmaceutical products including vaccines, biologics and cell therapies. Importantly, these pharmaceuticals are non-personalised and thus able to broadly impact the needs of oncology patients.
They are looking for a highly motivated Associate Scientist, early in their career, who wants to develop a deep passion for mass spectrometry-based proteomics/immunopeptidomics, applied to the exciting field of immuno-oncology. This entrepreneurial scientist will benefit from full training in all relevant techniques, in order to generate proteomic and immunopeptidome datasets from primary tissue samples using Ervaxx’s LC-MS/MS platforms. He/she will be responsible for keeping accurate records and to support the maintenance of the mass spec platforms, as well as, the general running of the laboratory.
The Associate Scientist will be expected to:
- Contribute technically to immunopeptidomic experiments and to analyze, interpret and communicate their data
- Maintain instrumentation and ensure smooth running of the laboratory.
- Perform to the highest standards of safety, quality and reproducibility
- Document their experiments and findings according high industrial standards to support and enable filing of patents and regulatory documents.
- Contribute to a vibrant and innovative working environment where new ideas are freely shared, developed and adopted among the teams.
- The Associate Scientist will make a major contribution to identify the most immunogenic antigens for incorporation into vaccines and potentially biologics or cell therapies to make a meaningful difference for patients suffering from cancer.
The ideal candidate will have:
- A BSc/MSc in a relevant scientific discipline.
- At least 1+ years’ hand-on experience in relevant biochemical techniques.
- Knowledge in mass spectrometry and liquid chromatography is a plus.
- Basic cell culturing skills is a plus.
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